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    Serum amyloid A (SAA) is a precursor of tissue amyloid A, similar to C-reactive protein (CRP), an acute-phase reactive protein produced by liver cells. SAA exists in a constant amount in the serum of normal people, but SAA can increase hundreds to thousands of times within 48-72h in the acute phase of inflammation or infection, and it decreases rapidly in the recovery phase of the disease. It is a more sensitive diagnosis than CRP. A marker of bacterial or viral infection.

    Clinical significance

    1. Prompt inflammatory response and identify the type of infection;

    2. A strong marker of cardiovascular mortality;

    3. Sensitive markers for monitoring transplant rejection;

    4. Early diagnosis and identification of infectious diseases in children.

    Profile of SAA